Interstate 80 westbound from Laramie is now open, according to the Wyoming Highway Patrol.
The Highway Patrol has reduced speeds near the crash scene to 65 mph, according to the news release from Patrol Sgt. David Wagener.
The Wyoming Department of Transportation has determined that 220 linear feed of roadway was damaged by the fire that happened during the crash on Monday.
Crews have been able to make emergency repairs to the damaged roadway.
The Highway Patrol asks motorists to slow down and follow the warnings because debris and work crews are still in the area.
Eastbound I-80 was reopened late Monday.
The crash involving 64 vehicles happened at 8 a.m. Monday when two commercial vehicles collided causing one of the trucks to jacknife in both westbound lanes. A chain reaction began, with several vehicles catching fire.
Two people died in the crash. One man was arrested and charged with aggravated vehicular homicide.