CASPER, Wyo. (AP) — Health officials say at least six people in the Casper area have been hospitalized for kidney failure after smoking the drug spice.

Three of those people are said to be in life-threatening condition from using the synthetic drug which mimics the effects of marijuana.

The Wyoming Department of Health issued a statewide warning about the drug Thursday. Department spokeswoman Kim Deti  says health officials can’t assume that the tainted batch of blueberry-flavored spice is only in the Casper area.

Casper Police Chief Chris Walsh says one patient was transferred to a Denver hospital with full kidney failure. Walsh says those sickened were between the ages of 15 and their mid-20s.